The DDZ is an interdisciplinary research center which combines molecular, clinical, and epidemiological work to improve prevention, early detection, diagnosis, and therapy of diabetes mellitus and its associated secondary complications.
The DDZ contributes to an improved quality of epidemiological data regarding diabetes in Germany. Moreover, the DDZ conducts clinical studies in order to analyze onset and development of diabetes, and to develop new prevention therapies. It represents the national reference center for diabetes research of the Leibniz-Association. As a result, the DDZ provides accurate scientific information related to diabetes mellitus for the public and for experts within the health care system.
The DDZ is operated through the non-profit German Diabetes Research Foundation (Deutsche Diabetes Forschungsgesellschaft e.V.), and is affiliated with the Heinrich-Heine-University Düsseldorf. The DDZ is also partner within the German Center for Diabetes Research (DZD), a research cluster of five institutions funded by the Federal Ministry of Education and Research.
The global proliferation of overweight and obese people and people with type 2 diabetes is often associated with the consumption of saturated fats. Scientists at the German Diabetes Center (Deutsches Diabetes-Zentrum, DDZ) and the Helmholtz Center in Munich (HMGU) have found that even the one-off consumption of a greater amount of palm oil reduces the body’s sensitivity to insulin and causes increased fat deposits as well as changes in the energy metabolism of the liver. The results of the study provide information on the earliest changes in the metabolism of the liver that in the long-term lead to fatty liver disease in overweight persons as well as in those with type 2 diabetes.
Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes. Scientists of Helmholtz Zentrum München, in collaboration with colleagues of the German Center for Diabetes Research (DZD), reported these results in the journal 'Diabetes'.
Who can participate:
- Patients with recently diagnosed type 1 or type 2 diabetes (less than 12 months since diagnosis)
- Patients between 18 and 69 years of age
The HIT study aims at investigating the short-term and long-term effects of a high-intensity intervall training on insulin sensitivity. We are looking for male overweight patients with type 2 diabetes (BMI > 25 kg/m²) and healthy, lean men at the age of 50-65 years. more...
In BARIATRIX-Study, we investigate the short-, intermediate- and long-term effects of bariatric surgery on energy metabolism and insulin sensitivity of severely obese patients. more...
Women with gestational diabetes face a clearly increased risk for type 2 diabetes. Therefore, this study re-examines patients with gestational diabetes up to ten years postpartum in order to assess the diabetes risk and to define preventive steps. more...