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The DDZ is an interdisciplinary research center which combines molecular, clinical, and epidemiological work to improve prevention, early detection, diagnosis, and therapy of diabetes mellitus and its associated secondary complications. The DDZ contributes to an improved quality of epidemiological data regarding diabetes in Germany. Moreover, the DDZ conducts clinical studies in order to analyze onset and development of diabetes, and to develop new prevention therapies.
The DDZ represents the national reference center for diabetes research of the Leibniz-Association. As a result, the DDZ provides accurate scientific information related to diabetes mellitus for the public and for experts within the health care system.
The DDZ is operated through the non-profit German Diabetes Research Foundation (Deutsche Diabetes Forschungsgesellschaft e.V.), and is affiliated with the Heinrich-Heine-University Düsseldorf. The DDZ is also partner within the German Center for Diabetes Research (DZD), a research cluster of five institutions funded by the Federal Ministry of Education and Research.
Scientists from Düsseldorf show that increased fat burning by the liver causes stress response, which explains the relationship between overweight, insulin resistance and fatty liver diseases. These findings present a novel approach for the prevention and treatment of fatty liver diseases.
The HIT study aims at investigating the short-term and long-term effects of a high-intensity intervall training on insulin sensitivity. We are looking for male overweight patients with type 2 diabetes (BMI > 25 kg/m²) and healthy, lean men at the age of 50-65 years. more...
Who can participate:
- Patients with recently diagnosed type 1 or type 2 diabetes (less than 12 months since diagnosis)
- Patients between 18 and 69 years of age
In BARIATRIX-Study, we investigate the short-, intermediate- and long-term effects of bariatric surgery on energy metabolism and insulin sensitivity of severely obese patients. more...
The PLIS Study (Prediabetes Lifestyle Intervention Study) aims at identifying the intensity of lifestyle intervention necessary for reducing the risk of type 2 diabetes in high-risk individuals. As a participant, you receive among other things individualized dietary and physical activity counseling. more...
Women with gestational diabetes face a clearly increased risk for type 2 diabetes. Therefore, this study re-examines patients with gestational diabetes up to ten years postpartum in order to assess the diabetes risk and to define preventive steps. more...